HCID 22915156, compound → HCID 54000870, compound

HRID 1456341Notes

Reaction equation

HRID 1456341 reaction equation
[N:1]([C:4]([C:11]1[S:15][C:14]([CH3:16])=[N:13][C:12]=1[CH3:17])([C:6]1[S:7][CH:8]=[CH:9][N:10]=1)[CH3:5])=[N+]=[N-]>C(O)C.[Pd]>[CH3:16][C:14]1[S:15][C:11]([C:4]([NH2:1])([C:6]2[S:7][CH:8]=[CH:9][N:10]=2)[CH3:5])=[C:12]([CH3:17])[N:13]=1

Participants

4

Reactant 1

HCID 22915156HCID 22915156, compound

Product 1

HCID 54000870HCID 54000870, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

The product from Example 19 in ethanol was hydrogenated in the presence of 10% palladium-on-charcoal to give the title compound. 1H Nmr (CDCl3) 2.02, 2.08 and 2.61 (each 3H, s), 2.23 (2H, br s) and 7.28 and 7.73 (each 1H, d, J 3 Hz) ppm.

Sources & evidence

ORD record
ord-127e73afd7df4687a6971bd5286e5854
Source dataset
uspto-grants-1998_12
Patent number
US05843971

Reaction notes

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