Dichloromethane → 5-(5-Chloro-4-(piperidin-4-ylmethylamino)pyridin-2-ylamino)pyrazine-2-carbonitrile
Reaction equation
[Cl:39][CH2:40][Cl:41].[Cl:8][c:9]1[c:10]([NH:24][CH2:25][CH:26]2[CH2:27][CH2:28][N:29]([C:32]([O:33][C:34]([CH3:35])([CH3:36])[CH3:37])=[O:38])[CH2:30][CH2:31]2)[cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][c:19]([C:22]#[N:23])[n:20][cH:21]2)[n:13][cH:14]1.[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[Cl:8][c:9]1[c:10]([NH:24][CH2:25][CH:26]2[CH2:27][CH2:28][NH:29][CH2:30][CH2:31]2)[cH:11][c:12]([NH:15][c:16]2[n:17][cH:18][c:19]([C:22]#[N:23])[n:20][cH:21]2)[n:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-ea117608115e405ea9e014b5fc6bb2fd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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