Hydrochloric Acid → HCID 67694283, compound

Participants

Reaction Steps

1.34 g of (2R,4R)-2-[2-{4-fluoro-2-[2-(3-methoxyphenyl)ethyl]phenoxy}-ethyl]-4-lauroyloxy-1-methylpyrrolidine [prepared as described in step (a) above] were dissolved in 15 ml of dioxane, and 0.90 ml of a 4N solution of hydrogen chloride in dioxane was added to the resulting solution. The solution was then concentrated by evaporation under reduced pressure. The resulting residue was purified by decantation three times with hexane, and the resulting oily substance was dried in vacuo, to give 1.39 g (yield 97%) of the title compound as a colorless oily substance.

Provenance & Evidence