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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1456662Generated: November 1, 2026

Trifluoroacetic acid → ((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetic Acid

https://huagongshe.com/reaction/1456662

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetic Acid t-Butyl EsterHCID 54431002—
SolventDichloromethaneHCID 6344—
Product((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetic AcidHCID 54183224—

Reaction Steps

To a solution of compound 723 (240 mg, 0.53 mmol) in CH2Cl2 (4.0 mL) was added TFA (2.0 mL) and the reaction stirred at rt for 1 hr. The reaction was concentrated in vacuo and the residue co-concentrated with toluene. The material was used directly in the next reaction without further purification. ##STR103##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05843904
Source datasetuspto-grants-1998_12
ORD IDord-d05609d843c44467bfbbb62272369a9e
Source noteuspto-grants-1998_12