HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → ((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | ((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetic Acid t-Butyl Ester | HCID 54431002 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | ((2(S)-Benzoylamino-3-methylbutyryl)indan-2-ylamino)acetic Acid | HCID 54183224 | — |
Reaction Steps
To a solution of compound 723 (240 mg, 0.53 mmol) in CH2Cl2 (4.0 mL) was added TFA (2.0 mL) and the reaction stirred at rt for 1 hr. The reaction was concentrated in vacuo and the residue co-concentrated with toluene. The material was used directly in the next reaction without further purification. ##STR103##
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05843904 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-d05609d843c44467bfbbb62272369a9e |
| Source note | uspto-grants-1998_12 |