HRID1456667

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID243

Benzoic acid

C7H6O2

HCID8357

3,4,5-Trimethoxybenzoic acid

C10H12O5

结构：CC(C)[C@H](NC(=O)c1ccccc1)C(=O)N(CC(=O)OC(C)(C)C)C1Cc2ccccc2C1

HCID54431002

未命名化合物

PRODUCTS

生成物

结构：COc1cc(C(=O)N[C@H](C(=O)N(CC(=O)O)C2Cc3ccccc3C2)C(C)C)cc(OC)c1OC

HCID54205516

未命名化合物

PROCEDURE

实验过程

Compound 730 was prepared by a method similar to the method used to prepare compound 724, except benzoic acid is replaced with 3,4,5-trimethoxybenzoic acid in the preparation of 723. ##STR109##

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5a04e788029a40328fa9500db5808028
来源数据集: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05843904
来源说明: uspto-grants-1998_12

反应 SMILES

C(O)(=O)C1C=CC=CC=1.[CH3:10][O:11][C:12]1[CH:13]=[C:14]([CH:18]=[C:19]([O:23][CH3:24])[C:20]=1[O:21][CH3:22])[C:15]([OH:17])=O.C([O:29][C:30](=[O:57])[CH2:31][N:32]([C:42](=[O:56])[C@@H:43]([NH:47]C(=O)C1C=CC=CC=1)[CH:44]([CH3:46])[CH3:45])[CH:33]1[CH2:41][C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH2:34]1)(C)(C)C>>[CH3:24][O:23][C:19]1[CH:18]=[C:14]([CH:13]=[C:12]([O:11][CH3:10])[C:20]=1[O:21][CH3:22])[C:15]([NH:47][C@@H:43]([CH:44]([CH3:46])[CH3:45])[C:42]([N:32]([CH2:31][C:30]([OH:57])=[O:29])[CH:33]1[CH2:41][C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[CH2:34]1)=[O:56])=[O:17]