Acetone → 4-Ethynylphenol

HRID 1456898Notes

Reaction equation

HRID 1456898 reaction equation
[C:1](=O)([O-])[O-].[K+].[K+].[I-].[K+].[C:9](OC(=O)CCl)([CH3:12])([CH3:11])[CH3:10].[CH3:18][C:19]([CH3:21])=[O:20]>>[CH:1]#[C:12][C:9]1[CH:10]=[CH:21][C:19]([OH:20])=[CH:18][CH:11]=1

Participants

5

Reactant 4

HCID 180AcetoneHCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 66052tert-Butyl chloroacetate

Product 1

HCID 327584-Ethynylphenol

Procedure

50.0 g of the resin synthesized in Reference Example 13 was dissolved in 500 ml of acetone. After adding 9.4 g of potassium carbonate, 1.9 g of potassium iodide and 8.5 g of tert-butylchloroacetate, the solution obtained was refluxed for 10 hours. Thereafter, same post-treatment as those in Reference Example 15 was repeated to obtain poly(p-vinylphenol), wherein 12% of the hydroxyl groups were ethyletherified and 14% of the hydroxyl groups were tert-butoxycarbonylmethyletherified. The weight average molecular weight of this resin is 15,000 and its molecular weight distribution is 1.28.

Workup

  1. customthe solution obtained
  2. temperaturewas refluxed for 10 hours

Sources & evidence

ORD record
ord-099f62910e584947815a1df21d8e06df
Source dataset
uspto-grants-1998_12
Patent number
US05846688

Reaction notes

Loading…