HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-4-piperidone → 7-Fluoro-3-(1,2,3,6-tetrahydro-1-methyl-4-pyridinyl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-4-piperidone | HCID 74049 | — |
| Reactant | 7-Fluoro-1H-indole | HCID 2774504 | — |
| Product | 7-Fluoro-3-(1,2,3,6-tetrahydro-1-methyl-4-pyridinyl)-1H-indole | HCID 18797158 | 75.1% |
Reaction Steps
Beginning with 0.50 gm (3.70 mMol) 7-fluoro-1H-indole and 0.91 mL (7.4 mMol) 1-methyl-4-piperidone, 0.64 gm (75%) of the title compound were recovered as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05846982 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-857368048ea142e4994883d1f6094dc7 |
| Source note | uspto-grants-1998_12 |