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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1456986Generated: October 30, 2026

7-chloro-1H-indole → 7-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

https://huagongshe.com/reaction/1456986

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-chloro-1H-indoleHCID 104644—
ReactantPiperonylamineHCID 2723901—
Product7-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 1854584975%

Reaction Steps

Beginning with 0.70 gm (4.6 mMol) 7-chloro-1H-indole and 1.4 gm (9.2 mMol) 4-piperidone hydrochloride monohydrate, 0.80 gm (75%) of the title compound were recovered as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05846982
Source datasetuspto-grants-1998_12
ORD IDord-eb5f300aca564dad9e015a880de01ee6
Source noteuspto-grants-1998_12