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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1456995Generated: November 1, 2026

1H-Indole, 6-methyl- → 6-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole

https://huagongshe.com/reaction/1456995

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Indole, 6-methyl-HCID 137928—
ReactantPiperonylamineHCID 2723901—
Product6-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 1042072622%

Reaction Steps

Beginning with 3.0 gm (28.0 mMol) 6-methyl-1H-indole and 7.04 gm (45.7 mMol) 4-piperidone hydrochloride monohydrate, 1.1 gm (22%) of the title compound were recovered as a tan powder.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05846982
Source datasetuspto-grants-1998_12
ORD IDord-7bb73860a30842248a55f3b11d13e2e7
Source noteuspto-grants-1998_12