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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1457047Generated: October 31, 2026

Methyl 3-(chlorosulfonyl)propanoate → Methyl 3-[2-[2-(4-methylphenyl)ethoxy]ethylaminosulphonyl]propanoate

https://huagongshe.com/reaction/1457047

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-(chlorosulfonyl)propanoateHCID 4962888—
Reactant2-[2-(4-Methylphenyl)ethoxy]ethanamine hydrochlorideHCID 18779075—
SolventDichloromethaneHCID 6344—
ProductMethyl 3-[2-[2-(4-methylphenyl)ethoxy]ethylaminosulphonyl]propanoateHCID 1877903446.6%

Reaction Steps

The subtitle compound (2.49 g) was prepared according to the procedure in example 5 part d using 2-[2-(4-methylphenyl)ethoxy]ethanamine hydrochloride (3.5 g) triethylamine 4.74 ml) methyl 3-(chlorosulphonyl)propanoate (3.08 g), and dichloromethane (80 ml).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05846989
Source datasetuspto-grants-1998_12
ORD IDord-26e8bcc0681a4542908a8ce25098b437
Source noteuspto-grants-1998_12