4-Aminopyridine → HCID 21221625, compound

HRID 1457079Notes

Reaction equation

HRID 1457079 reaction equation
[CH3:1][N:2]([CH3:19])[CH:3]1[CH2:18][CH2:17][C:6]2[O:7][C:8]3[CH:13]=[CH:12][C:11]([C:14](Cl)=[O:15])=[CH:10][C:9]=3[C:5]=2[CH2:4]1.[NH2:20][C:21]1[CH:26]=[CH:25][N:24]=[CH:23][CH:22]=1>>[N:24]1[CH:25]=[CH:26][C:21]([NH:20][C:14]([C:11]2[CH:12]=[CH:13][C:8]3[O:7][C:6]4[CH2:17][CH2:18][CH:3]([N:2]([CH3:19])[CH3:1])[CH2:4][C:5]=4[C:9]=3[CH:10]=2)=[O:15])=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 17274-AminopyridineHCID 21221671HCID 21221671, compound

Product 1

HCID 21221625HCID 21221625, compoundYield 38.8%

Procedure

Beginning with 0.011 gm (0.04 mMol) 2-dimethylamino-1,2,3,4-tetrahydrodibenzofuran-8-carbonyl chloride and 0.08 mMol 4-aminopyridine, 0.0052 gm (37%) of the title compound were recovered.

Sources & evidence

ORD record
ord-9df1bd268cf44991ae31d8c84c4d3aff
Source dataset
uspto-grants-1998_12
Patent number
US05846995

Reaction notes

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