1,1-Dimethylethyl 3,3-dimethyl-2-oxo-1-piperidinecarboxylate → 3,3-Dimethylpiperidin-2-one

Participants

Reaction Steps

The title compound of Step (B) (440 mg, 1.94 mmol) in 4 ml MeOH and 15 ml 1N HCl in Et2O was stirred at room temperature overnight. The solvent was evaporated and dried in vacuo to provide the title compound of this step as a light yellow solid which was relatively pure and was used in the next step without further purification.

Provenance & Evidence