Phenethylamine → HCID 86753416, compound

HRID 1457308Notes

Reaction equation

HRID 1457308 reaction equation
CO[C:3](=[O:22])[C@H:4]([CH2:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)[NH:5][C:6]([NH:8][C:9]1[S:10][C:11](=[S:14])[NH:12][N:13]=1)=[O:7].[CH2:23]([NH2:31])[CH2:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[S:14]=[C:11]1[S:10][C:9]([NH:8][C:6]([NH:5][C@@H:4]([CH2:15][CH:16]2[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]2)[C:3]([NH:31][CH2:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[O:22])=[O:7])=[N:13][NH:12]1

Participants

3

Reactant 2

HCID 1001PhenethylamineHCID 10712490HCID 10712490, compound

Product 1

HCID 86753416HCID 86753416, compound

Procedure

Following the general procedure outlined in EXAMPLE 5, and making non-critical variations but starting with N-[[(4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl)amino]carbonyl]-β-cyclohexyl-L-alanine methyl ester (prepared similarly to that described in EXAMPLE 1) and phenethylamine, the title compound is obtained (mp 199°-200° C.).

Workup

  1. customprepared similarly to

Sources & evidence

ORD record
ord-be5679672872497ca51e7dd792e912bb
Source dataset
uspto-grants-1998_12
Patent number
US05847148

Reaction notes

Loading…