Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1457518Generated: October 31, 2026

Iodine → HCID 131720978, compound

https://huagongshe.com/reaction/1457518

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodineHCID 807—
ReactantNinhydrinHCID 10236—
ReactantBiotinHCID 171548—
ReactantHCID 131720979HCID 131720979—
SolventChloroform methanolHCID 21584188—
ProductHCID 131720978HCID 131720978—

Reaction Steps

Silica gel thin layer chromatography, in 8/2 chloroform/methanol and visualized with iodine and ninhydrin spray, was used at various stages of the synthesis to show disappearance of the starting amine and appearance of the biotin acid derivative.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05849599
Source datasetuspto-grants-1998_12
ORD IDord-4dd653f2b4774a02a9452b2a4903294a
Source noteuspto-grants-1998_12