Hydrochloric Acid → HCID 70128325, compound

HRID 1457526Notes

Reaction equation

HRID 1457526 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[C:11]2[C:19]3[C:14](=[CH:15][CH:16]=[C:17]([C:20](=[O:28])[CH2:21][N:22]4[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]4)[CH:18]=3)[NH:13][C:12]2=[O:29])=[CH:2]1.[ClH:30]>O>[ClH:30].[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([CH:10]=[C:11]2[C:19]3[C:14](=[CH:15][CH:16]=[C:17]([C:20](=[O:28])[CH2:21][N:22]4[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]4)[CH:18]=3)[NH:13][C:12]2=[O:29])=[CH:2]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 54364444HCID 54364444, compound

Product 1

HCID 70128325HCID 70128325, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a suspension of 3-(indol-3-ylmethylene)-5-(2-piperidin-1-yl-acetyl)-2-indolinone (100 mg) in water (10 ml) the stoichiometric amount of 0,1N HCl solution (3 ml) was added. The solution was freeze-dried to give 105 mg of 3-(indol-3-ylmethylene)-5-(2-piperidin-1-yl-acetyl)-2-indolinone hydrochloride.

Workup

  1. additionwas added
  2. customThe solution was freeze-dried

Sources & evidence

ORD record
ord-4a9d9a14d99b46998e7af0ee658bf58b
Source dataset
uspto-grants-1998_12
Patent number
US05849710

Reaction notes

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