Sodium Nitrate → 6-trifluoroacetamido-7-nitro-2,3(1H,4H)-quinoxalinedione

Participants

Reaction Steps

A solution of 39 g (0.14 mol) of 6-trifluoroacetamidoquinoxaline -2,3(1H,4H)-dione in 500 ml of concentrated sulfuric acid was cooled to 0° C., 12.1 g (0.14 mol) of sodium nitrate were added in portions, and the mixture was stirred at room temperature for 30 minutes. It was subsequently poured into ice-water and the crude product was filtered off and worked up by conventional methods. Yield: 95%. Melting point >320° C.

Provenance & Evidence