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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1457587Generated: October 30, 2026

Phosgene → {2-[3-((1S)-1-methoxycarbonyl-2-phenylethyl)ureido]-4-methoxy-6-tert-butylphenoxy}methoxymethane

https://huagongshe.com/reaction/1457587

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosgeneHCID 6371—
ReactantL-Phenylalanine, methyl esterHCID 736234—
Reactant(2-Amino-4-methoxy-6-tert-butylphenoxy)methoxymethaneHCID 18765846—
Product{2-[3-((1S)-1-methoxycarbonyl-2-phenylethyl)ureido]-4-methoxy-6-tert-butylphenoxy}methoxymethaneHCID 67694345—

Reaction Steps

(2-Amino-4-methoxy-6-tert-butylphenoxy)methoxymethane, phosgene and L-phenylalanine methyl ester were treated in the same manner as described in Example 16 (1) to give {2-[3-((1S)-1-methoxycarbonyl-2-phenylethyl)ureido]-4-methoxy-6-tert-butylphenoxy}methoxymethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05849732
Source datasetuspto-grants-1998_12
ORD IDord-e4572efd9c7141f39f4453fc3477b317
Source noteuspto-grants-1998_12