HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 18784500, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Propanoic acid, 2-methyl-3-oxo-, methyl ester | HCID 103507 | — |
| Reactant | 4-Fluorobenzamidine Hydrochloride | HCID 12456160 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 18784500 | HCID 18784500 | — |
Reaction Steps
Sodium hydride (0.52 g, 13 mmol) is added to 20 mL of anhydrous ethanol and stirred for 30 minutes at ambient temperature. To this, 4-fluorobenzamidine hydrochloride (1.47 g, 8.5 mmol) (from example 40) is added and the mixture is stirred for further 30 minutes. Methyl 2-formylpropionate (1 g, 10.6 mmol) is added dropwise and the reaction mixture is left for 4 days under stirring at ambient temperature.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05849758 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-360a814081644a2ebcf5256a04442bb4 |
| Source note | uspto-grants-1998_12 |