Methylamine → HCID 59896603, compound

HRID 1457909Notes

Reaction equation

HRID 1457909 reaction equation
[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:9](SC)=[CH:10][N+:11]([O-:13])=[O:12])=[CH:4][CH:3]=1.[CH3:16][NH2:17]>CCO.CO>[Cl:1][C:2]1[N:7]=[CH:6][C:5]([NH:8][C:9]([NH:17][CH3:16])=[CH:10][N+:11]([O-:13])=[O:12])=[CH:4][CH:3]=1

Participants

5

Reactant 2

HCID 6329MethylamineHCID 85593012HCID 85593012, compound

Product 1

HCID 59896603HCID 59896603, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

In 25 ml of EtOH was dissolved 0.42 g (0.00171 mole) of 1-(6-chloro-3-pyridyl)amino-1-methylthio-2-nitroethylene, followed by addition of 0.2 g of a 40% solution of methylamine in methanol. The mixture was refluxed for 1.5 hours. The solvent was distilled off and the crystalline residue was washed with AcOEt and dried to recover 0.33 g of the title compound as white crystals.

Workup

  1. temperatureThe mixture was refluxed for 1.5 hours
  2. distillationThe solvent was distilled off
  3. washthe crystalline residue was washed with AcOEt
  4. customdried
  5. customto recover 0.33 g of the title compound as white crystals

Sources & evidence

ORD record
ord-2d20ea13f1604c998e6cf31029b21c2f
Source dataset
uspto-grants-1998_12
Patent number
US05849768

Reaction notes

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