Hydrochloric Acid → 4-chloro-2-methyl-5-(methylsulfonyl)Benzoic acid

HRID 1457943Notes

Reaction equation

HRID 1457943 reaction equation
[CH3:1][C:2]1[CH:11]=[C:10]([Cl:12])[C:9]([S:13]([CH3:16])(=[O:15])=[O:14])=[CH:8][C:3]=1[C:4]([O:6]C)=[O:5].Cl>CO>[CH3:1][C:2]1[CH:11]=[C:10]([Cl:12])[C:9]([S:13]([CH3:16])(=[O:15])=[O:14])=[CH:8][C:3]=1[C:4]([OH:6])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 10611543HCID 10611543, compound

Product 1

HCID 108244784-chloro-2-methyl-5-(methylsulfonyl)Benzoic acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

10 g of methyl 2-methyl-4-chloro-5-methylsulphonylbenzoate are added, while cooling with ice, to a mixture of 30 ml of conc. HCl and 200 ml of methanol, and the whole is then stirred for 2 h. The resulting precipitate is filtered off with suction and recrystallized from methanol. 2-Methyl-4-chloro-5-methylsulphonylbenzoic acid is obtained, m.p. 217°-218°.

Workup

  1. filtrationThe resulting precipitate is filtered off with suction
  2. customrecrystallized from methanol

Sources & evidence

ORD record
ord-48be71f96c0c4e1fb0d4d286672daded
Source dataset
uspto-grants-1998_12
Patent number
US05849796

Reaction notes

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