Benzyl chloroformate → HCID 53928292, compound

HRID 1457962Notes

Reaction equation

HRID 1457962 reaction equation
C1([C@H]([N:9]2[CH2:13][CH2:12][C@H:11]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:10]2)C)C=CC=CC=1.[C:20](Cl)(=[O:29])[O:21][CH2:22][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:22]([O:21][C:20]([N:9]1[CH2:13][CH2:12][C@H:11]([CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])[CH2:10]1)=[O:29])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 10387Benzyl chloroformateHCID 14975361HCID 14975361, compound

Product 1

HCID 53928292HCID 53928292, compound

Procedure

(3R)-Ethyl 1-[(R)-1-phenylethyl]pyrrolidine-3-acetate described in U.S. Pat. No. 621,101 is allowed to react with benzyl chlorocarbonate to give (3R)-ethyl 1-benzyloxycarbonylpyrrolidine-3-acetate.

Sources & evidence

ORD record
ord-ed9836e0e0314d5f86cd5a6cdb75c12d
Source dataset
uspto-grants-1998_12
Patent number
US05849757

Reaction notes

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