Benzyl Bromide → HCID 22100535, compound

HRID 1457966Notes

Reaction equation

HRID 1457966 reaction equation
[C:1]([O:5][C:6]([NH:8][C:9]1([CH:13]2[CH2:17][NH:16][C:15](=[O:18])[CH2:14]2)[CH2:12][CH2:11][CH2:10]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:19](Br)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.C(Cl)C1C=CC=CC=1>>[CH2:19]([N:16]1[CH2:17][CH:13]([C:9]2([NH:8][C:6]([O:5][C:1]([CH3:4])([CH3:2])[CH3:3])=[O:7])[CH2:12][CH2:11][CH2:10]2)[CH2:14][C:15]1=[O:18])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

4

Reactant 3

HCID 7498Benzyl BromideHCID 7503Benzyl ChlorideHCID 11777088HCID 11777088, compound

Product 1

HCID 22100535HCID 22100535, compound

Procedure

Next, 4-(1-tert-butoxycarbonylaminocyclobutyl)-2-pyrrolidone is allowed to react with benzyl bromide or benzyl chloride using a base to yield 1-benzyl-4-(1-tert-butoxycarbonylaminocyclobutyl)-2-pyrrolidone.

Sources & evidence

ORD record
ord-64c52dcd682c44d985011e5d0abeb642
Source dataset
uspto-grants-1998_12
Patent number
US05849757

Reaction notes

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