HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 10979461, compound → HCID 53977651, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 10979461 | HCID 10979461 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 53977651 | HCID 53977651 | 99% |
Reaction Steps
A 13.1 g (43.8 mmol) portion of 4-(1-ethoxycarbonylcyclopropyl)-1-[(S)-1-phenylethyl]-3-pyrrolin-2-one was dissolved 300 ml of methanol, mixed with 400 mg of platinum oxide and then stirred in an atmosphere of hydrogen for 18 hours. After completion of the reaction, the reaction solution was filtered and concentrated to yield 13.0 g (99 %) of the titled compound as an oily substance.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05849757 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-9bdf700c106e43c1b7ad1e4d40ec9bd7 |
| Source note | uspto-grants-1998_12 |