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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1458221Generated: November 2, 2026

Pyridine → HCID 53801641, compound

https://huagongshe.com/reaction/1458221

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridineHCID 1049—
ReactantAcetyl chlorideHCID 6367—
ReactantHCID 22101805HCID 22101805—
SolventDichloromethaneHCID 6344—
ProductHCID 53801641HCID 53801641—

Reaction Steps

Acetyl chloride (0.6 ml) was added to a solution of 1-(4-methyl-5-thiazolyl) -1-phenylmethanol (800 mg) and pyridine (0.5 ml) in dichloromethane (30 ml) at 0° C. under an atmosphere of dry nitrogen. The mixture was allowed to warm room temperature and was then stirred overnight. Evaporation and purification of the residue by flash chromatography gave the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05849921
Source datasetuspto-grants-1998_12
ORD IDord-013f25c79ae5421887108219013dde81
Source noteuspto-grants-1998_12