HCID 22101833, compound → HCID 22101855, compound

Participants

Reaction Steps

1-(4-Methyl-5-thiazolyl)-1-(3-nitrophenyl)methanol (2 g) and 10% palladium on charcoal (200 mg) in ethanol (60 ml) were shaken overnight under an atmosphere of hydrogen. The mixture was filtered and the filtrate was evaporated to dryness. The residue was converted into the hydrochloride salt, recrystallised and then reconverted into the title compound. M.p. 137°-138° C.

Provenance & Evidence