Hydrazine hydrate (1:1) → HCID 18689516, compound

HRID 1458245Notes

Reaction equation

HRID 1458245 reaction equation
O.[NH2:2][NH2:3].Cl[C:5]1[C:10]([C:11]([F:14])([F:13])[F:12])=[CH:9][C:8]([Cl:15])=[C:7]([O:16][CH2:17][C:18]#[CH:19])[N:6]=1>>[Cl:15][C:8]1[C:7]([O:16][CH2:17][C:18]#[CH:19])=[N:6][C:5]([NH:2][NH2:3])=[C:10]([C:11]([F:14])([F:13])[F:12])[CH:9]=1

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 18689506HCID 18689506, compound

Product 1

HCID 18689516HCID 18689516, compound

Procedure

Starting from 7.8 g (0.155 mol) of hydrazine hydrate and 20 g (0.074 mol) of 2, 5-dichloro-6-propargyloxy-3-trifluoromethylpyridine, 11.0 g (56% of theory) of the title compound were obtained as a colorless powder of m.p. 98°-102° C. (Table II, No. 2.036) under the conditions of Example III.4.

Sources & evidence

ORD record
ord-dd118956667c4ac5b62d3a6dae13ec9c
Source dataset
uspto-grants-1998_12
Patent number
US05849920

Reaction notes

Loading…