HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2Z)-4-hydroxy-2-[4-(methylsulfonyl)phenyl]-3-phenylbut-2-enyl acetate → (Z)-4-Acetoxy-3-(4-(Methylsulfonyl)Phenyl)-2-Phenyl-2-Butenal
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2Z)-4-hydroxy-2-[4-(methylsulfonyl)phenyl]-3-phenylbut-2-enyl acetate | HCID 58787789 | — |
| Catalyst | Manganese dioxide | HCID 14801 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (Z)-4-Acetoxy-3-(4-(Methylsulfonyl)Phenyl)-2-Phenyl-2-Butenal | HCID 86753445 | 74.8% |
Reaction Steps
A mixture of the acetate from Example 2 (215 mg) and MnO2 (1.2 g) in 30 mL of CH2Cl2 was stirred for 12 h at r.t., and then filtered through a pad of celite. The filtrate was concentrated to give 160 mg of the title compound as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05849943 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-15f6d70ffffc420eb899293d64cc0176 |
| Source note | uspto-grants-1998_12 |