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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1458316Generated: November 4, 2026

(2Z)-4-hydroxy-2-[4-(methylsulfonyl)phenyl]-3-phenylbut-2-enyl acetate → (Z)-4-Acetoxy-3-(4-(Methylsulfonyl)Phenyl)-2-Phenyl-2-Butenal

https://huagongshe.com/reaction/1458316

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2Z)-4-hydroxy-2-[4-(methylsulfonyl)phenyl]-3-phenylbut-2-enyl acetateHCID 58787789—
CatalystManganese dioxideHCID 14801—
SolventDichloromethaneHCID 6344—
Product(Z)-4-Acetoxy-3-(4-(Methylsulfonyl)Phenyl)-2-Phenyl-2-ButenalHCID 8675344574.8%

Reaction Steps

A mixture of the acetate from Example 2 (215 mg) and MnO2 (1.2 g) in 30 mL of CH2Cl2 was stirred for 12 h at r.t., and then filtered through a pad of celite. The filtrate was concentrated to give 160 mg of the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05849943
Source datasetuspto-grants-1998_12
ORD IDord-15f6d70ffffc420eb899293d64cc0176
Source noteuspto-grants-1998_12