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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1458323Generated: October 26, 2026

2-Trimethylsilyloxy-4-(4-(methylthio)phenyl)-3,4-dihydrofuran → 4-(4-(methylthio)phenyl)-2-(5H)-furanone

https://huagongshe.com/reaction/1458323

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Trimethylsilyloxy-4-(4-(methylthio)phenyl)-3,4-dihydrofuranHCID 18400192—
Catalystpalladium(II) acetateHCID 167845—
SolventAcetonitrileHCID 6342—
Product4-(4-(methylthio)phenyl)-2-(5H)-furanoneHCID 12150589—

Reaction Steps

To a solution of 4 g of Pd(OAc)2 in 100 ml of acetonitrile is added dropwise the crude product from Step 1 (5 g) under nitrogen at r.t.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05849943
Source datasetuspto-grants-1998_12
ORD IDord-5a913cedc42643bbbcdf388f077798c9
Source noteuspto-grants-1998_12