2-Trimethylsilyloxy-4-(4-(methylthio)phenyl)-3,4-dihydrofuran → 4-(4-(methylthio)phenyl)-2-(5H)-furanone

HRID 1458323노트

반응식

HRID 1458323 반응식
C[Si](C)(C)[O:3][CH:4]1[CH2:8][CH:7]([C:9]2[CH:14]=[CH:13][C:12]([S:15][CH3:16])=[CH:11][CH:10]=2)[CH2:6][O:5]1>C(#N)C.CC([O-])=O.CC([O-])=O.[Pd+2]>[CH3:16][S:15][C:12]1[CH:13]=[CH:14][C:9]([C:7]2[CH2:6][O:5][C:4](=[O:3])[CH:8]=2)=[CH:10][CH:11]=1

참가 물질

4

반응물 1

HCID 184001922-Trimethylsilyloxy-4-(4-(methylthio)phenyl)-3,4-dihydrofuran

생성물 1

HCID 121505894-(4-(methylthio)phenyl)-2-(5H)-furanone

시약·촉매·용매 2

HCID 167845palladium(II) acetate촉매HCID 6342Acetonitrile용매

실험 절차

To a solution of 4 g of Pd(OAc)2 in 100 ml of acetonitrile is added dropwise the crude product from Step 1 (5 g) under nitrogen at r.t.

출처 및 근거

ORD 기록
ord-5a913cedc42643bbbcdf388f077798c9
출처 데이터셋
uspto-grants-1998_12
특허 번호
US05849943

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