Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Benzoic acid, 4-[[bis(2-chloroethyl)amino]methyl]- | HCID 425503 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 85981973 | HCID 85981973 | — |
Reaction Steps
Thionyl chloride (1 ml) was added to a solution of 320 mg (1.0 mmol) of 4-[N,N-bis(2-chloroethyl)aminomethyl]benzoic acid in 2 ml of benzene, followed by stirring under heating at 80° C. for 2 hours. After the solvent was distilled out under reduced pressure, the residue was dried up under reduced pressure so that a white solid was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05852011 |
|---|
| Source dataset | uspto-grants-1998_12 |
|---|
| ORD ID | ord-03b1b8bd10af44afa0107c13917c6dc6 |
|---|
| Source note | uspto-grants-1998_12 |
|---|
