Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethanolamine | HCID 8113 | — |
| Reactant | Benzene, 1-fluoro-2-methyl-4-nitro- | HCID 68001 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 22096784 | HCID 22096784 | 83.9% |
Reaction Steps
In 30 ml of DMSO, 4.0 g (25.8 mmol) of 2-fluoro-5-nitrotoluene and 7.0 g (67 mmol) of diethanolamine were dissolved. The resultant solution was stirred under heat at 140° C. for 6.5 hours, followed by extraction with ethyl acetate. The solvent was distilled out under reduced pressure. The residue so obtained was washed with ethyl acetate, whereby 5.2 g of the title compound were obtained as yellow powder (yield: 84%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05852011 |
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| Source dataset | uspto-grants-1998_12 |
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| ORD ID | ord-d90e30cb18d64f77869ff3d205249e60 |
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| Source note | uspto-grants-1998_12 |
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