Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethanolamine | HCID 8113 | — |
| Reactant | 5-Fluoro-2-nitrotoluene | HCID 94956 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 22096786 | HCID 22096786 | 65.2% |
Reaction Steps
In 8 ml of DMSO, 5.0 g (64.5 mmol) of 2-nitro-5-fluorotoluene and 8.2 g (78 mmol) of diethanolamine were dissolved. The resultant solution was stirred under heat at 140° C. for 7 hours, followed by extraction with ethyl acetate. After the solvent was distilled out under reduced pressure, the residue was washed with ethyl acetate, whereby 10.1 g of yellow powder were obtained (yield: 65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05852011 |
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| Source dataset | uspto-grants-1998_12 |
|---|
| ORD ID | ord-69b9bd8b1e7b43a4b6329d385353c35c |
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| Source note | uspto-grants-1998_12 |
|---|
