Diethyl Oxalate → 6-(1-Pyrrolyl)-7-trifluoromethyl-2,3(1H,4H)-quinoxalinedione

HRID 1458794Notes

Reaction equation

HRID 1458794 reaction equation
[F:1][C:2]([F:17])([F:16])[C:3]1[CH:8]=[C:7]([NH2:9])[C:6]([NH2:10])=[CH:5][C:4]=1[N:11]1[CH:15]=[CH:14][CH:13]=[CH:12]1.[C:18](OCC)(=[O:24])[C:19](OCC)=[O:20]>>[N:11]1([C:4]2[CH:5]=[C:6]3[C:7](=[CH:8][C:3]=2[C:2]([F:1])([F:16])[F:17])[NH:9][C:19](=[O:20])[C:18](=[O:24])[NH:10]3)[CH:12]=[CH:13][CH:14]=[CH:15]1

Participants

3

Reactant 2

HCID 7268Diethyl OxalateHCID 22097153N-(2-trifluoromethyl-4,5-diaminophenyl)pyrrole

Product 1

HCID 220970866-(1-Pyrrolyl)-7-trifluoromethyl-2,3(1H,4H)-quinoxalinedione

Procedure

This compound was prepared by the method of Example 1f from 0.8 g (3.3 mmol) of N-(2-trifluoromethyl-4,5-diaminophenyl)pyrrole and 32 g (221 mmol) of diethyl oxalate.

Sources & evidence

ORD record
ord-79cf501d4a3943eb9313f9bdeb558268
Source dataset
uspto-grants-1998_12
Patent number
US05852017

Reaction notes

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