6-trifluoroacetamido-7-nitro-2,3(1H,4H)-quinoxalinedione → 6-Amino-7-nitroquinoxaline-2,3-diol

HRID 1458802Notes

Reaction equation

HRID 1458802 reaction equation
FC(F)(F)C([NH:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][C:15]=1[N+:16]([O-:18])=[O:17])[NH:12][C:11](=[O:19])[C:10](=[O:20])[NH:9]2)=O>C(O)C.Cl>[NH2:5][C:6]1[CH:7]=[C:8]2[C:13](=[CH:14][C:15]=1[N+:16]([O-:18])=[O:17])[NH:12][C:11](=[O:19])[C:10](=[O:20])[NH:9]2

Participants

4

Reactant 1

HCID 220971576-trifluoroacetamido-7-nitro-2,3(1H,4H)-quinoxalinedione

Product 1

HCID 39809926-Amino-7-nitroquinoxaline-2,3-diol

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 702EthanolSolvent

Procedure

A solution of 41 g (0.13 mol) of 6-trifluoroacetamido-7-nitro-2,3(1H,4H)-quinoxalinedione in 300 ml of ethanol and 700 ml of 3 molar hydrochloric acid was refluxed for 3 hours. The reaction mixture was cooled, and the crude product was filtered off and worked up by conventional methods.

Workup

  1. temperatureThe reaction mixture was cooled
  2. filtrationthe crude product was filtered off

Sources & evidence

ORD record
ord-74c9d7a26eff4994ba5d9dd16048ada7
Source dataset
uspto-grants-1998_12
Patent number
US05852017

Reaction notes

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