Dimethylformamide → HCID 22097106, compound

HRID 1458832Notes

Reaction equation

HRID 1458832 reaction equation
[CH2:1]([N:3]1[C:12]2[C:7](=[CH:8][C:9]([N+]([O-])=O)=[CH:10][CH:11]=2)[NH:6][C:5](=[O:16])[C:4]1=[O:17])[CH3:2].C[N:19](C)C=O>[Pd]>[NH2:19][C:10]1[CH:11]=[C:12]2[C:7]([NH:6][C:5](=[O:16])[C:4](=[O:17])[N:3]2[CH2:1][CH3:2])=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 6228DimethylformamideHCID 19702951HCID 19702951, compound

Product 1

HCID 22097106HCID 22097106, compoundYield 81%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

8.3 g (35 mmol) of 1-ethyl-6-nitro-2,3 (1H,4H)-quinoxalinedione were dissolved in 300 ml of dimethylformamide and, after addition of 2 g of palladium/carbon (10%), were hydrogenated. The mixture was then filtered and the filtrate was concentrated under reduced pressure to yield 5.9 g (81%) of the product.

Workup

  1. filtrationThe mixture was then filtered
  2. concentrationthe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-99be0419559e4f22931e81c94f3ca831
Source dataset
uspto-grants-1998_12
Patent number
US05852017

Reaction notes

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