1-Naphthaldehyde → HCID 22876507, compound

Participants

Reaction Steps

Using (S)-prolinol ((S)-VIII-1) and α-naphthoaldehyde as the starting materials, a similar operation was carried out to obtain (S)-N-(α-naphthyl)methyl-2-pyrrolidine methanol ((S)-II-2). ##STR316## [α] D20 65.6° (C=0.16, CH3OH) IR spectrum (NaCl) νmax cm-1 : 3400, 3040, 2950, 2870, 1600, 1500, 1460, 1350, 1170, 1040, 800, 790, 780 1H-NMR (CDCl3) δ ppm :7.25-8.30 (7 H, m, aromatic-H), 2.60-4.55 (7 H, m, other -H), 2.35 (1 H, br, OH), 1.65-2.01 (4 H, m, C--CH2CH2 --C)

Provenance & Evidence