2-Amino-5-methylpyridine → HCID 178475856, compound

HRID 1459177Notes

Reaction equation

HRID 1459177 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N=C1CC(C)CCN1.[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([CH3:20])=[CH:16][N:15]=1>>[C:1]([OH:4])(=[O:3])[CH3:2].[NH:13]=[C:14]1[CH2:19][CH2:18][CH:17]([CH3:20])[CH2:16][NH:15]1

Participants

3

Reactant 2

HCID 153482-Amino-5-methylpyridineHCID 1784758702-Imino-4-methylpiperidine acetate

Product 1

HCID 178475856HCID 178475856, compound

Procedure

The method of preparation of 2-imino-4-methylpiperidine acetate, EXAMPLE 6, was used to convert 2-amino-5-methylpyridine to the title compound which was obtained as a white solid. The analysis of the product was found to be consistent with the proposed structure. m.p. 175°-178° C. MH+=113; d1H NMR (D2O): δ3.28-3.21 (m, 1H); 2.79-2.70 (m, 1H); 2.49-2.43 (m, 2H); 1.79-1.67 (m, 2H); 1.73 (s, 3H); 1.30-1.23 (m, 1H); 0.82 (d, J=6.6 Hz, 3H).

Sources & evidence

ORD record
ord-b562d9238f7e45bb9df0c9d894230af4
Source dataset
uspto-grants-1998_12
Patent number
US05854234

Reaction notes

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