Dichloromethane → (1,4-Diazepan-1-yl)(tetrahydro-2H-pyran-4-yl)methanone

HRID 145941Notes

Reaction equation

HRID 145941 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([C:15](=[O:16])[CH:17]2[CH2:18][CH2:19][O:20][CH2:21][CH2:22]2)[CH2:12][CH2:13][CH2:14]1)([CH3:5])([CH3:6])[CH3:7].[Cl:30][CH2:31][Cl:32].[OH:23][C:24]([C:25]([F:26])([F:27])[F:28])=[O:29]>>[NH:8]1[CH2:9][CH2:10][N:11]([C:15](=[O:16])[CH:17]2[CH2:18][CH2:19][O:20][CH2:21][CH2:22]2)[CH2:12][CH2:13][CH2:14]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 591433904-(Tetrahydro-pyran-4-carbonyl)-[1,4]diazepane-1-carboxylic acid tert-butyl ester

Product 1

HCID 28776660(1,4-Diazepan-1-yl)(tetrahydro-2H-pyran-4-yl)methanone

Sources & evidence

ORD record
ord-2ec840736afb45bb9deef4c6173fb857
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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