Acetic Anhydride → HCID 54201469, compound

HRID 1459675Notes

Reaction equation

[CH:1]1[C:11]2[CH2:10][NH:9][C:8]3[CH:12]=[CH:13][CH:14]=[C:15]([NH:16][S:17]([C:20]4[CH:25]=[CH:24][C:23]([O:26][CH3:27])=[CH:22][CH:21]=4)(=[O:19])=[O:18])[C:7]=3[NH:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[C:28](OC(=O)C)(=[O:30])[CH3:29]>>[C:28]([N:9]1[CH2:10][C:11]2[CH:1]=[CH:2][CH:3]=[CH:4][C:5]=2[NH:6][C:7]2[C:15]([NH:16][S:17]([C:20]3[CH:21]=[CH:22][C:23]([O:26][CH3:27])=[CH:24][CH:25]=3)(=[O:19])=[O:18])=[CH:14][CH:13]=[CH:12][C:8]1=2)(=[O:30])[CH3:29]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 54030760HCID 54030760, compound

Product 1

HCID 54201469HCID 54201469, compound

Procedure

N-(10,11-Dihydro-5H-dibenzo(b,e)(1,4)diazepin-6-yl)-4-methoxybenzensulfonamide, which had been synthesized in the same manner as the one of Example 31, was reacted with acetic anhydride at room temperature. Then the obtained product was purified by silica gel column chromatography and thus the title compound was obtained.

Workup

customThen the obtained product was purified by silica gel column chromatography

Sources & evidence

ORD record: ord-422d9deff1bb46e693a5f634ec9f9b72
Source dataset: uspto-grants-1998_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05854274

Reaction notes

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