HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1,2,4-Triazol-1-yl)aniline → 2-[5-(1,2,4-Triazol-1-yl)-1H-indol-3-yl]ethyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1,2,4-Triazol-1-yl)aniline | HCID 735826 | — |
| Reactant | 1H-Indole-3-ethanol, 5-(4H-1,2,4-triazol-4-yl)- | HCID 10561309 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-[5-(1,2,4-Triazol-1-yl)-1H-indol-3-yl]ethyl alcohol | HCID 54274611 | — |
Reaction Steps
Prepared from 4-(1,2,4-triazol-1-yl)aniline (EP497512) as described for Intermediate 3, δ (250 MHz, D6 -DMSO) 2.89 (2H, t, J=7.2 Hz, CH2), 3.64-3.74 (2H, m, CH2), 4.67 (1H, t, J=5.3 Hz, OH), 7.29 (1H, d, J=2.3 Hz, Ar--H), 7.47 (1H, dd, J=8.7 and 1.5 Hz, Ar--H), 7.53 (1H, dd, J=8.7 and 2.3 Hz, Ar--H), 7.95 (1H, d, J=1.9 Hz, Ar--H), 8.19 (1H, s, Ar--H), 9.19 (1H, s, Ar--H), 11.10 (1H, s, NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05854268 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-830f590d4af34156b125bce62add5e95 |
| Source note | uspto-grants-1998_12 |