HRID1459712

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID320165

4-(1H-imidazol-1-yl)aniline

C9H9N3

HCID10561309

1H-Indole-3-ethanol, 5-(4H-1,2,4-triazol-4-yl)-

C12H12N4O

PRODUCTS

生成物

HCID69101157

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID679

Dimethyl sulfoxide

C2H6OS

PROCEDURE

实验过程

Prepared from 4-(imidazol-1-yl)aniline (EP497512) as described for Intermediate 3, δ (360 MHz, D6 -DMSO) 2.87 (2H, t, J=7.2 Hz, CH2), 3.64-3.70 (1H, m, CH2 --OH), 4.61 (1H, t, J=5.3 Hz, OH), 7.08 (1H, s, Ar--H), 7.25-7.27 (2H, m, Ar--H), 7.44 (1H, d, J=8.8 Hz, Ar--H), 7.64 (1H, d, J=2.5 Hz, Ar--H), 7.70 (1H, d, J=2.1 Hz, Ar--H), 8.11 (1H, s, Ar--H), 11.00 (1H, s, NH), m/e 228 (M+1)+.