HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1H-imidazol-1-yl)aniline → 2-[5-(Imidazol-1-yl)-1H-indol-3-yl]ethyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1H-imidazol-1-yl)aniline | HCID 320165 | — |
| Reactant | 1H-Indole-3-ethanol, 5-(4H-1,2,4-triazol-4-yl)- | HCID 10561309 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | 2-[5-(Imidazol-1-yl)-1H-indol-3-yl]ethyl alcohol | HCID 69101157 | — |
Reaction Steps
Prepared from 4-(imidazol-1-yl)aniline (EP497512) as described for Intermediate 3, δ (360 MHz, D6 -DMSO) 2.87 (2H, t, J=7.2 Hz, CH2), 3.64-3.70 (1H, m, CH2 --OH), 4.61 (1H, t, J=5.3 Hz, OH), 7.08 (1H, s, Ar--H), 7.25-7.27 (2H, m, Ar--H), 7.44 (1H, d, J=8.8 Hz, Ar--H), 7.64 (1H, d, J=2.5 Hz, Ar--H), 7.70 (1H, d, J=2.1 Hz, Ar--H), 8.11 (1H, s, Ar--H), 11.00 (1H, s, NH), m/e 228 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05854268 |
| Source dataset | uspto-grants-1998_12 |
| ORD ID | ord-c6cd66eaa9c04cce9732d1f926b06a3e |
| Source note | uspto-grants-1998_12 |