反应详情

温度

90 °C

To 4-(2-chloro-phenoxy)-butyric acid (250 mg, 1.165 mmol) was added portion wise thionyl chloride (1.69 mL), and the reaction mixture was stirred for 3 hours at 90° C. After such time the excess of thionyl chloride was removed in vacuo to yield the crude title compound which was used in the next step without any further purification.

1. customAfter such time the excess of thionyl chloride was removed in vacuo