HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 14599Generated: October 27, 2026
Thionyl Chloride → 4-(2-Chloro-phenoxy)-butyryl chloride
https://huagongshe.com/reaction/14599
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-(2-Chlorophenoxy)butanoic acid | HCID 3014343 | — |
| Product | 4-(2-Chloro-phenoxy)-butyryl chloride | HCID 13721442 | — |
Reaction Steps
To 4-(2-chloro-phenoxy)-butyric acid (250 mg, 1.165 mmol) was added portion wise thionyl chloride (1.69 mL), and the reaction mixture was stirred for 3 hours at 90° C. After such time the excess of thionyl chloride was removed in vacuo to yield the crude title compound which was used in the next step without any further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07732452B2 |
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| Source dataset | uspto-grants-2010_06 |
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| ORD ID | ord-fde6eab1543d4615a8db0d0b3ab8f6db |
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| Source note | uspto-grants-2010_06 |
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