Dimethylformamide dimethyl acetal → HCID 15670823, compound

HRID 1460148Notes

Reaction equation

HRID 1460148 reaction equation
[NH2:1][C:2]1[C:18]([Cl:19])=[CH:17][C:5]([C:6]([NH:8][CH:9]2[CH:14]3[CH2:15][CH2:16][N:11]([CH2:12][CH2:13]3)[CH2:10]2)=[O:7])=[C:4]([OH:20])[CH:3]=1.CO[CH:23](OC)[N:24]([CH3:26])[CH3:25]>>[N:11]12[CH2:12][CH2:13][CH:14]([CH2:15][CH2:16]1)[CH:9]([NH:8][C:6](=[O:7])[C:5]1[CH:17]=[C:18]([Cl:19])[C:2]([N:1]=[CH:23][N:24]([CH3:26])[CH3:25])=[CH:3][C:4]=1[OH:20])[CH2:10]2

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 156708204-Amino-N-(1-azabicyclo[2.2.2]octan-3-yl)-5-chloro-2-hydroxybenzamide

Product 1

HCID 15670823HCID 15670823, compound

Procedure

Following the procedure of Example 1, the title compound is prepared from 4-amino-N-(1-azabicyclo[2.2.2]oct-3-yl)-5-chloro-2-hydroxybenzamide and N,N-dimethylformamide dimethylacetal.

Sources & evidence

ORD record
ord-61f0c6fe44a84c0ba04978a09214f136
Source dataset
uspto-grants-1991_12
Patent number
US05070095

Reaction notes

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