Benzaldehyde → HCID 67946032, compound

HRID 1460201Notes

Reaction equation

[ClH:1].[NH:2]1[C:10]23[CH2:11][CH2:12][CH2:13][CH2:14][C:5]2([CH2:6][CH2:7][C:8]2[CH:18]=[CH:17][CH:16]=[CH:15][C:9]=23)[CH2:4][CH2:3]1.[CH:19](=O)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[ClH:1].[C:20]1([CH2:19][N:2]2[C:10]34[CH2:11][CH2:12][CH2:13][CH2:14][C:5]3([CH2:6][CH2:7][C:8]3[CH:18]=[CH:17][CH:16]=[CH:15][C:9]=34)[CH2:4][CH2:3]2)[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 67946049HCID 67946049, compound

Product 1

HCID 67946032HCID 67946032, compoundYield 42%

Procedure

In a manner similar to that described in Example 32, the product from Example 23 (0.34 g, 1.50 mmol) and benzaldehyde are reacted. Workup, followed crystallization from ether and HCl gave the title compound (0 22 g, 42%) as a white solid mp 235-237° C.

Workup

customcrystallization from ether and HCl

Sources & evidence

ORD record: ord-935612ab2b9c4eab8fa9f85fe72e8bd7
Source dataset: uspto-grants-1991_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05070093

Reaction notes

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