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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1460235Generated: November 1, 2026

Benzenesulfonyl chloride → Ethyl 1-(phenylsulfonyl)piperidine-4-carboxylate

https://huagongshe.com/reaction/1460235

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenesulfonyl chlorideHCID 7369—
ReactantEthyl 4-piperidinecarboxylateHCID 70770—
ProductEthyl 1-(phenylsulfonyl)piperidine-4-carboxylateHCID 25710378%

Reaction Steps

In another preparation, 100 g (0.634 mole) of ethyl isonipecotate and 130.4 g (0.74 mole) of benzenesulfonyl chloride were reacted by the above procedure for 4.5 hr to give the title product in 78% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05070087
Source datasetuspto-grants-1991_12
ORD IDord-b9cd770a4fc644069907a552deaf4752
Source noteuspto-grants-1991_12