反应详情

To a mixture of 44 g of 5-nitro-2-chlorobenzenesulfonyl chloride and 100 ml of dichloromethane, was added dropwise a dichloromethane solution containing 48.4 g of methyloctadecylamine and 36.1 ml of triethylamine. After completion of the reaction, the reaction solvent was removed by distillation under reduced pressure, and 300 ml of methanol was added to the residue. The mixture was once heated to dissolve, and then gradually cooled to precipitate crystals, which were collected by filtration and dried to yield 64 g (74%) of the noted compound.

1. customAfter completion of the reaction
2. customthe reaction solvent was removed by distillation under reduced pressure, and 300 ml of methanol
3. additionwas added to the residue
4. temperatureThe mixture was once heated
5. dissolutionto dissolve
6. temperaturegradually cooled
7. customto precipitate crystals, which
8. filtrationwere collected by filtration
9. customdried