HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Pyrimidinyl)piperazine → HCID 15020939, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Pyrimidinyl)piperazine | HCID 88747 | — |
| Reactant | HCID 15020879 | HCID 15020879 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 15020939 | HCID 15020939 | 79% |
Reaction Steps
A 202 mg amount of the compound of Example 13 was dissolved in 20 ml of dioxane, and 242 mg (3 equivalents) of 1-(2-pyrimidinyl)piperazine was added, followed by heating under reflux for 7 hours. The reaction treatment and purification were conducted as in Example 75, to give 195 mg of the desired compound (yield 79%). The maleic acid salt was obtained in a conventional manner.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05071845 |
| Source dataset | uspto-grants-1991_12 |
| ORD ID | ord-b985701d027346faa03eb0d84bec6af7 |
| Source note | uspto-grants-1991_12 |