Phosphorus oxychloride → HCID 178432280, 화합물

HRID 1460446노트

반응식

HRID 1460446 반응식
[C:1]([C:4]1[N:5]=[CH:6][N:7]2[C:12]([OH:13])=[C:11]([CH2:14][CH2:15]O)[C:10]([CH3:17])=[N:9][C:8]=12)(=O)[NH2:2].P(Cl)(Cl)([Cl:20])=O>>[Cl:20][CH2:15][CH2:14][C:11]1[C:10]([CH3:17])=[N:9][C:8]2[N:7]([CH:6]=[N:5][C:4]=2[C:1]#[N:2])[C:12]=1[OH:13]

참가 물질

3

반응물 2

HCID 24813Phosphorus oxychlorideHCID 178432286HCID 178432286, 화합물

생성물 1

HCID 178432280HCID 178432280, 화합물

실험 절차

0.17 mol of the compound obtained in Stage A of Example 3, dissolved in 200 ml of phosphorus oxychloride, is brought to 85° C. for one hour 30 minutes. The phosphorus oxychloride is then removed by evaporation under vacuum. 100 ml of water are added and the pH is adjusted to 7 using sodium bicarbonate to crystallize the expected compound. The latter is filtered off.

후처리

  1. customThe phosphorus oxychloride is then removed by evaporation under vacuum
  2. addition100 ml of water are added
  3. customto crystallize the expected compound
  4. filtrationThe latter is filtered off

출처 및 근거

ORD 기록
ord-cd433cea569546cb94c49cc2779f9b0e
출처 데이터셋
uspto-grants-1991_12
특허 번호
US05071847

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